Marburg virus

Cameroonian authorities detected two suspected cases of Marburg disease on Monday in Olamze, a commune on the border with Equatorial Guinea, ...

The World Health Organization says that Marburg, an Ebola-related virus, caused at least nine deaths in the tiny Western African country.

Seven people died who were exposed to the virus while conducting research on monkeys. Last year, there were two reported Marburg deaths in Ghana. Without treatment, Marburg can be fatal in up to 88% of people. The WHO said there were currently nine deaths and 16 suspected cases with symptoms including fever, fatigue, diarrhea and vomiting. In a statement on Monday, the U.N. [Bats Are the Number-One Carriers of Disease](https://time.com/4827511/bats-viruses-diseases-pandemic/)

Closely related to Ebola, the Marburg virus has killed at least nine people in Equatorial Guinea. Its symptoms include severe hemorrhaging.

WHO announced that Equatorial Guinea confirmed its first outbreak of the rare disease.

[the African fruit batopens in a new tab or window](https://www.cdc.gov/vhf/marburg/transmission/index.html), a sighted cave-dwelling bat found across Africa. Around day 5 of symptoms, a maculopapular rash, most prominent on the trunk, may occur. Other symptoms may include nausea, vomiting, chest pain, sore throat, abdominal pain, and diarrhea. [fatality rateopens in a new tab or window](https://www.cdc.gov/vhf/marburg/symptoms/index.html) is 23% to 90%. [Marburg virus vaccine consortiumopens in a new tab or window](https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010805) (MARVAC). [incubation periodopens in a new tab or window](https://www.cdc.gov/vhf/marburg/symptoms/index.html) for Marburg virus disease is 2 to 21 days. In addition, 15 cases occurred in Uganda in 2012. [Supportive therapyopens in a new tab or window](https://www.cdc.gov/vhf/marburg/treatment/index.html) should be used in the hospital, including balancing the patient's fluids and electrolytes, maintaining oxygen status and blood pressure, replacing lost blood and clotting factors, and treatment for any complicating infections. [according to the CDCopens in a new tab or window](https://www.cdc.gov/vhf/marburg/outbreaks/chronology.html). Fruit bats do not show signs of infection. [sub-Saharan Africaopens in a new tab or window](https://www.cdc.gov/vhf/marburg/outbreaks/distribution-map.html), and the rare case in travelers, mostly returning from African countries. [antiviral treatmentopens in a new tab or window](https://www.cdc.gov/vhf/marburg/treatment/index.html) for this hemorrhagic fever, which can cause severe illness and death.

The World Health Organization convened an urgent meeting to evaluate vaccine candidates after nine deaths and 16 suspected cases were reported.

The organization said it will work with clinicians and health officials in Equatorial Guinea to determine what a trial might look like. Attendees at the WHO meeting discussed five vaccine candidates that have shown promise against Marburg virus in animal studies. [according to the Centers for Disease Control and Prevention](https://www.cdc.gov/vhf/marburg/symptoms/index.html). Before this, the most recent Marburg outbreak was in Ghana in July. George Ameh, the WHO’s representative in Equatorial Guinea, said the organization has ramped up contact tracing. On Tuesday, the WHO convened an urgent meeting to evaluate several possible vaccine candidates that could be administered during the outbreak.

Equatorial Guinea has reported nine deaths and sixteen suspected cases of Marbug virus disease, and Cameroon has reported an additional two suspected cases, ...

[few hundred readily available doses](https://www.statnews.com/2023/02/14/marburg-outbreak-race-to-test-vaccines-drugs/), according the Helen Braswell, reporting on an [emergency meeting of the World Health Organization](https://www.who.int/news-room/events/detail/2023/02/14/default-calendar/who-urgent-marburg-meeting). [basic reproduction number (R0) was measured to be around 1.6](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050948) for the 2005 outbreak in Angola, similar to that of seasonal influenza. Peak infectiousness is estimated to be reached around [10 days since infection](https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050948). Although the area of Cameroon where the two suspected cases were identified is adjacent to the presumptive origin in Equatorial Guinea, it is worrying that [neither case had a travel history](https://www.reuters.com/world/africa/who-increasing-health-surveillance-after-equatorial-guinea-finds-marburg-virus-2023-02-14/), suggesting that unobserved local transmission may be ongoing in both countries. In only four of these outbreaks did the number of cases reach double digits, but two were quite large (154 cases in the Democratic Republic of the Congo in 1998-2000 and 252 cases in Angola in 2004-2005), showing that sustained transmission is possible. It is probable that additional cases will be discovered. The present one creates the possibility of testing those vaccines in the field, but deployment would need to be immediate and with such a small outbreak it is hard to guess what distribution would be optimal. I’m a scientist. Past spillover events have occurred in Angola, the Democratic Republic of Congo, Ghana, Guinea, Kenya, Uganda, and Zimbabwe, showing that Marburg is not geographically isolated. Unfortunately, supplies are limited to only a This means that the raw case fatality rate is about 80%. Outbreaks are believed to start with the spillover of the virus from fruit bats into human population.

Cameroonian authorities detected two suspected cases of Marburg disease on Monday in Olamze, a commune on the border with Equatorial Guinea, the public ...

“On the 13th of February, we had two suspected cases. There are no vaccines or antiviral treatments approved to treat it. Cameroonian authorities detected two suspected cases of Marburg disease on Monday in Olamze, a commune on the border with Equatorial Guinea, the public health delegate for the region, Robert Mathurin Bidjang, said on Tuesday.

Control measures such as quarantine could end the outbreak in Equatorial Guinea quickly — good news for inhabitants but a mixed blessing for clinical ...

It’s good news for public health and the people of Equatorial Guinea, but perhaps bad news for science.” None of the vaccines is available in large quantities, developers said at the meeting: availability ranges from a few hundred doses in the case of the Sabin and PHV vaccines to a few thousand for Janssen’s candidate. At this week’s WHO meeting, officials discussed the practicalities of testing Marburg virus vaccines in Equatorial Guinea.

Marburg virus causes severe viral hemorrhagic fever and 24% to 88% of people who contracted the disease in different outbreaks died.

[may appear](https://www.cdc.gov/vhf/marburg/symptoms/index.html). We need an improvement in diagnosis which can help us do the detection as quickly, and as efficiently as possible. And once that is done – as with Ebola – the person must immediately be isolated and avoid contact with other people. Arrivals from Ghana and other West African countries must be checked at the ports of entry. Serological [studies](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968259/) have also revealed evidence of past Marburg virus infection in Nigeria. This leads me to believe that the virus is probably more widespread than we think it is. [first reported](https://www.who.int/news-room/fact-sheets/detail/marburg-virus-disease) in 1967 in a town called Marburg in Germany and in Belgrade, Yugoslavia (now Serbia). It is spread through contact with materials (fluids, blood, tissues and cells) of an infected host or reservoir. Given that there have been cases in Ghana, it's time to be on the alert. It has varied [between](https://www.cdc.gov/vhf/marburg/index.html) 24% to 88% in different outbreaks depending on virus strain and case management. The laboratory staff got infected as a result of working with materials (blood, tissues and cells) of the monkeys. The virus, which belongs to the same family as the Ebola virus, causes severe viral hemorrhagic fever in humans with an average case fatality rate of

News outlets report on a concerning outbreak of Marburg fever in Equatorial Guinea, which has prompted the World Health Organization to consider an ...

(Schnirring, 2/14) (2/14) According to a report from the Conflict Observatory, a State Department-supported initiative, Russia has placed at least 6,000 Ukrainian children at 43 camps and institutions stretching from Ukraine’s Russian-occupied Crimea region to Siberia and Russia’s Pacific coast, or with new families, as part of its “systematic, whole-of-government approach to the relocation, re-education and, in some cases, adoption and forced adoption of Ukrainian children.” (Ryan, 2/14) The meeting brought together a consortium of vaccine developers, researchers and government officials — a group the WHO created in 2021 to advance a Marburg vaccine. A Marburg fever outbreak in Equatorial Guinea is galvanizing efforts to test drugs and vaccines for a virus that currently has none. News outlets report on a concerning outbreak of Marburg fever in Equatorial Guinea, which has prompted the World Health Organization to consider an experimental vaccine.

Marburg virus causes severe viral hemorrhagic fever and 24% to 88% of people who contracted the disease in different outbreaks died.

[may appear](https://www.cdc.gov/vhf/marburg/symptoms/index.html). And once that is done – as with Ebola – the person must immediately be isolated and avoid contact with other people. Serological [studies](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968259/) have also revealed evidence of past Marburg virus infection in Nigeria. Arrivals from Ghana and other West African countries must be checked at the ports of entry. We need an improvement in diagnosis which can help us do the detection as quickly, and as efficiently as possible. [first reported](https://www.who.int/news-room/fact-sheets/detail/marburg-virus-disease) in 1967 in a town called Marburg in Germany and in Belgrade, Yugoslavia (now Serbia). It is spread through contact with materials (fluids, blood, tissues and cells) of an infected host or reservoir. Given that there have been cases in Ghana, it's time to be on the alert. It has varied [between](https://www.cdc.gov/vhf/marburg/index.html) 24% to 88% in different outbreaks depending on virus strain and case management. The laboratory staff got infected as a result of working with materials (blood, tissues and cells) of the monkeys. The virus, which belongs to the same family as the Ebola virus, causes severe viral hemorrhagic fever in humans with an average case fatality rate of The Conversation Africa's Wale Fatade and Usifo Omozokpea asked virologist Oyewale Tomori about its origin and how people can protect themselves against the disease after cases were [confirmed in Ghana in July 2022](https://www.bbc.com/news/world-africa-62202240).