Chiefs vs 49ers

Here are five things we'll be looking for during the course of the Kansas City Chiefs' Week 7 game against the San Francisco 49ers.

Even against a tough defensive front, the Chiefs need to find a way to get the running game going against the 49ers in Week 7. The 49ers have 23 total sacks as a team this season, good for second most in the NFL. Andy Reid and Kyle Shanahan are two of the most inventive offensive minds in the NFL. There are going to be opportunities in the passing game that Patrick Mahomes and the receivers will need to take advantage of. Since the start of the 2021 season, the Chiefs and 49ers have each scored 47 offensive TDs on plays featuring pre-snap motion. They surrendered 25 total pressures, including three sacks to the Bills in Week 6. They neglected the ground game against the Bills in Week 6. The play-calling must be more innovative when it comes to the ground game. The 49ers also suffered a letdown against the Falcons a week ago. The Chiefs are coming off of a disappointing loss to the Bills at home in Week 6. Early in the game, they played a lot of basic zone coverage looks because they simply didn’t have the personnel to do much else. Which team will manage to get back on schedule with a win in Week 7?

Anthony Dabbundo previews the Week 7 clash between the Kansas City Chiefs and San Francisco 49ers for Action Network.

The Chiefs however do rank 25th in Rushing Success Rate allowed and that will enable the 49ers to stay ahead of the sticks, use the clock and keep Mahomes off the field. Pressure has derailed the Chiefs offense at various points of the season and the 49ers will be able to get enough to slow down Mahomes on Sunday. Kansas City plays on the faster side, but they do play considerably slower in the second half (16th) than first (9th) In the world of totals, 49 is a key number, so I wouldn’t play it any lower than the current market offering. Both rank inside the top 15 in most pressures allowed and that’s a huge risk to drag this KC offense down. Now the 49ers will have star pass rusher Nick Bosa back for this game after he was a full participant in practice on Friday. Get up-to-the-minute [NFL odds here.](https://www.actionnetwork.com/nfl/odds) It’s an elite and well-coached defensive unit that is more than capable of taking away the middle of the field. [Panthers](https://www.actionnetwork.com/nfl/odds/carolina-panthers) running back Christian McCaffrey on Thursday. San Francisco’s move on Thursday clearly suggests that the Niners think they have the opportunity to make a deep playoff run in a wide open NFC, but the 49ers sit at just 3-3 through six weeks. The Chiefs have shown some cracks at various points of the first six weeks despite their 4-2 record. Despite that, the 49ers did receive some favorable injury news on Friday ahead of hosting the Chiefs on Sunday in a rematch of [Super Bowl](https://www.actionnetwork.com/nfl/futures/super-bowl-odds) LIV.

Let's look at the lists of inactive players for both the Kansas City Chiefs and the San Francisco 49ers for Week 7.

The Chiefs and 49ers are set to kick off at 3:25 p.m. That’s not to say that the Niners are at full strength. [San Francisco 49ers](https://ninernoise.com/) looked like they were the walking wounded.

The Chiefs and 49ers meet in Week 7 of the NFL season. We break down what we know before Week 7 inactives arrive at 2:55 p.m. ET on Sunday.

The Chiefs have a short injury list heading into this matchup. We will get the full list around 2:55 p.m. ET at Levi Stadium and the game will air on Fox.

. Kickoff is set for 3:25 p.m. on Sunday afternoon. The game will be broadcast on FOX — locally on WDAF/4. For the second time this season, the Chiefs are going ...

- Wk San Francisco head coach Kyle Shanahan was born eight years and one day after Reid’s PPK pass went “a little offline.” Kansas City hasn’t defeated San Francisco at home since December 6, 1971, when Len Dawson’s Chiefs defeated John Brodie’s 49ers 26-17. Meanwhile, San Francisco’s fell to 3-3 with a [28-14 road loss](https://www.ninersnation.com/2022/10/16/23407520/49ers-falcons-week-6-loss-game-recap) to the [Atlanta Falcons](https://www.thefalcoholic.com/). But in Week 2, Lance was lost for the season when he fractured his ankle during the team’s game against the [Seattle Seahawks](https://www.fieldgulls.com/). [NFL Draft](https://www.sbnation.com/nfl-draft) to select Marshall signal-caller Trey Lance, who then won San Francisco’s starting job. As the season began in San Francisco, however, it wasn’t clear that 31-year-old quarterback Jimmy Garoppolo would even be on the team in 2022. The teams continue to be led by the same quarterbacks. But this time, the revenge factor is with the home team, since the [Chiefs defeated the 49ers 31-20](https://www.arrowheadpride.com/2020/2/2/21119343/live-game-and-score-updates-no-score-in-the-first-quarter) in Super Bowl LIV to win their first NFL championship in 50 years. In Week 4, Kansas City avenged its The game will be broadcast on FOX — locally on WDAF/4.

Chiefs rookie RB Isiah Pacheco took the first-team reps in practice this week and is expected to be the starter over Clyde Edwards-Helaire, NFL Network ...

Pass protection is one of the places Pacheco has stood out, thanks in part to the schooling he received at Rutgers from then-RBs coach Augie Hoffmann, who was an NFL offensive lineman and now coaches the O-line at Rutgers. So backs must be able to have pass-protection proficiency and the ability to catch out of the backfield. But he's picked it up quickly in practice and dating back to training camp, sources say. Now it'll likely be Pacheco and Edwards-Helaire with a splash of McKinnon. [Isiah Pacheco](/players/isiah-pacheco/) took the first-team reps in practice this week and is expected to be the starter at running back in [Sunday's game](https://www.nfl.com/games/chiefs-at-49ers-2022-reg-7) vs. Pacheco will replace former first-rounder [Clyde Edwards-Helaire](/players/clyde-edwards-helaire/), who will still have a key role on offense.

What are some of the top Chiefs vs. 49ers player props to target for this week's game in San Francisco? We highlight some of our favorite bets.

Even if Samuel runs more routes than he has this season, which is still the vast majority of his snaps and touches, Aiyuk is in an excellent position to produce. That’s still great, but Mahomes throws the ball a ton, and the NFL’s No.1 defense in passing EPA will be swarming. Samuel’s seen his rushing responsibilities drop since 2021 and even the first three weeks of this year, with only two carries in each of the last three games. They’ve allowed an average of only 4.2 catches, 26.5 yards, and one-third of a touchdown to the tight end position this season. I don’t like his chances of reaching 16 or more yards if he has one or two carries since he’s averaged only seven yards a game over the last four weeks. He’s coming off his best game of the year, showing why fantasy pundits were all aboard his train entering the year. I think Kyle Shanahan knows it’s time for Deebo to be the excellent receiver he can be, first and foremost. I’m at the point where I’m betting on Kelce to score every week. His yardage has varied each week, sometimes in the 50s and other times over the century mark. Head over to FanDuel Sportsbook, where [you can get a no-sweat first bet up to $1,000](http://wlfanduel.adsrv.eacdn.com/C.ashx?btag=a_20412b_2425c_&affid=11558&siteid=20412&adid=2425&c=). [sports betting](https://www.profootballnetwork.com/nfl-cfb-betting/) aspects of this matchup, with lines courtesy of our friends at FanDuel Sportsbook. Of course, all eyes will be on whether new 49ers running back Christian McCaffrey can make an impact.

It's being reported by multiple sources this morning that the Chiefs' seventh-round rookie will get the starting nod today.

The Chiefs are tops in the league in scoring so far in 2022 and still trying to make tweaks to improve their offensive production as the season progresses. The move to start Pacheco should signal that Reid, Eric Bieniemy, and the offensive staff have clearly recognized a trend in how to unlock the best version of this Chiefs offense: establishing an aggressive rushing offense early. Not only does this move force the 49ers to be more patient in their pass rush as opposed to letting Nick Bosa and Drake Jackson pin their ears back and go, but it also put the guys up front in a more aggressive mindset.

Lightning-fast analysis of the Kansas City Chiefs' Week 7 game against the San Francisco 49ers.

- I was a little critical of the Chiefs’ pass rush in the first half, but they really came alive in the second half. - Steve Spagnuolo seems to get a little carried away with the blitz game at times. Everyone on the offensive side of the ball contributed in a meaningful way against a defense that was considered among the league’s best. - Both JuJu Smith-Schuster and Marquez Valdes-Scantling are really starting to settle into the offense. They stuck with it on both sides of the ball and ended up winning the game by over 20 points. They gave up big play after big play on defense, Patrick Mahomes threw first possession interception and suddenly they were down 10-0 in the first quarter.

Get a recap of the Kansas City Chiefs vs. San Francisco 49ers football game.

Coach Jim Harbaugh came back for the 10th anniversary of his team that went to the Super Bowl. Just explosive plays, one after another just keeping drives going and then them finding a way to get in the end zone.” [his early interception](https://twitter.com/49ers/status/1584283293238710272?s=20&t=5F0B698sMhxy5QcbxreI6A) putting Kansas City (5-2) in a 10-0 hole but that once again proved to be no problem as he led the Chiefs to touchdowns on six of the next seven drives. [Kansas City Chiefs](/nfl/team/_/name/kc/kansas-city-chiefs) needed to get going. “That’s just what the game felt like. They had one on Pat today. The Chiefs took control with back-to-back touchdown drives to start the second half. [Isiah Pacheco](https://www.espn.com/nfl/player/_/id/4361529/isiah-pacheco) and a personal foul on [Jauan Jennings](http://www.espn.com/nfl/player/_/id/3886598/jauan-jennings). “They have the X-factor on the quarterback. We came together as a team.” [Nick Bosa](https://www.espn.com/nfl/player/_/id/4040605/nick-bosa) said. “I guess we like challenging ourselves at this point.

All aspects of the Kansas City offense turned it on over the Niners for one of the most impressive performances of the NFL season.

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