Notre Dame linebacker JD Bertrand (27) and Notre Dame safety Xavier Watts (26) combine to tackle Stanford wide receiver Michael Wilson (4) during the Notre Dame ...
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SportsLine's model just revealed its CFB picks and best bets for Stanford Cardinal vs. Notre Dame Fighting Irish on Saturday, Oct. 15.
- Notre Dame vs. [Chris Tyree](/college-football/players/3171678/chris-tyree/) is a change-of-pace back for Notre Dame. Here are the [college football odds](https://www.sportsline.com/college-football/odds/) and betting lines for Notre Dame vs. [Audric Estime](/college-football/players/26713577/audric-estime/) is the leading tailback for the Fighting Irish. Notre Dame](https://www.sportsline.com/college-football/game-forecast/NCAAF_20221015_STNFRD@ND/) and just locked in its picks and CFB predictions. SportsLine's model is leaning Over on the total, projecting the teams to combine for 60 points. The Fighting Irish are 16.5-point favorites in the latest Notre Dame vs. [Stanford Cardinal](https://www.cbssports.com/college-football/teams/STNFRD/stanford-cardinal/) (1-4) and the [Notre Dame Fighting Irish](https://www.cbssports.com/college-football/teams/ND/notre-dame-fighting-irish/) (3-2) battling in prime time. [college football](/college-football/) game 10,000 times. Kickoff from Notre Dame Stadium in South Bend, Ind., is set for 7:30 p.m. Notre Dame picks, be sure to Last week, the Fighting Irish upset then-16t ranked [BYU](https://www.cbssports.com/college-football/teams/BYU/byu-cougars/) 28-20.