Bills

Will Buffalo end its two-game losing streak against Tennessee? Find out what the NFL's top analysts are predicting for Monday night's home opener.

The Titans have won the last two meetings, but those were home games. The Titans are coming off a brutal loss to the Giants where they blew a big lead. They should put up a better defensive effort against the Bills than the Rams did. I'm not sure the Titans will be able to keep up and score with the Bills offense. The Bills have the look of a potential juggernaut. I don't see the Titans as a playoff team, but there are a couple of coaches I generally ride with in the underdog role, and Mike Vrabel is one of them.

Our betting experts answer some of the most pressing questions surrounding Monday night's matchups between the Titans and Bills, and the Vikings and Eagles.

This sets the stage for [Treylon Burks](https://www.espn.com/nfl/player/_/id/4567156/treylon-burks) to make a huge impact. [Dallas Goedert](https://www.espn.com/nfl/player/_/id/3121023/dallas-goedert) under 48.5 receiving yards (-128). [Kirk Cousins](https://www.espn.com/nfl/player/_/id/14880/kirk-cousins) and [Justin Jefferson](https://www.espn.com/nfl/player/_/id/4262921/justin-jefferson) were clearly calibrated. Goedert is a solid tight end, for sure, but he's competing with Brown and [DeVonta Smith](https://www.espn.com/nfl/player/_/id/4241478/devonta-smith) for targets. [Jalen Hurts](https://www.espn.com/nfl/player/_/id/4040715/jalen-hurts) currently has the fifth-best odds to win MVP (+1400) ahead of [Lamar Jackson](https://www.espn.com/nfl/player/_/id/3916387/lamar-jackson) and behind [Tom Brady](https://www.espn.com/nfl/player/_/id/2330/tom-brady). [Aaron Rodgers](https://www.espn.com/nfl/player/_/id/8439/aaron-rodgers). [Rodger Saffold](https://www.espn.com/nfl/player/_/id/13294/rodger-saffold), but also the preseason injury to [Harold Landry III](https://www.espn.com/nfl/player/_/id/3122793/harold-landry) (maybe their most important defensive player). [Kyle Philips](https://www.espn.com/nfl/player/_/id/4367175/kyle-philips) may have led the Titans in targets, receptions and receiving yards in Week 1, but now he's questionable for this game with a shoulder injury. As a result of the Bills' defensive line overhaul that includes the offseason addition of [Von Miller](https://www.espn.com/nfl/player/_/id/13976/von-miller), they should be able to capitalize. Brown](https://www.espn.com/nfl/player/_/id/4047646/aj-brown) is no longer on the team, the Titans have become even more dependent on Henry. Throw in the [Kirk Cousins](https://www.espn.com/nfl/player/_/id/14880/kirk-cousins) "prime time" narrative and I'll play the Birds at less than a field goal. The Bills were able to move the ball at will in their opener, going the entire game without having to punt and putting 31 points on the board, but the total in that game was still only 41 points because of what their defense was able to do to the Rams' offense.

The Tennessee Titans will head out on the road to face off against the Buffalo Bills at 7:15 p.m. ET on Monday at Highmark Stadium. Coming off of a loss in a ...

[NFL picks](https://www.sportsline.com/nfl/picks/#ttag=SL19_lk_cbssports_nfl_htw) for every single game, including this one, from SportsLine's advanced computer model. - Oct 11, 2015 - Buffalo 14 vs. [Josh Allen](https://www.cbssports.com/nfl/players/playerpage/2181054) was slinging it as he passed for three TDs and 297 yards on 31 attempts in addition to rushing for one TD and 56 yards. - Oct 07, 2018 - Buffalo 13 vs. - Oct 06, 2019 - Buffalo 14 vs. Tennessee lost 21-20 to New York. Regional restrictions may apply.) It was a group effort with five guys contributing. - Oct 18, 2021 - Tennessee 34 vs. The oddsmakers were on Buffalo's side, but they didn't give the squad enough credit as the margin was unexpectedly wide. Their loss shouldn't obscure the performances of RB Coming off of a loss in a game they were expected to win, the Titans nows face the more daunting task of proving themselves against unfavorable odds.

Nashville, TN - In Week 6 of the 2021 season, the Tennessee Titans hosted the Buffalo Bills for a Monday Night Football contest and won by a score of.

Next, Buffalo recorded the game’s sixth lead change with a 75- yard scoring drive that culminated in a one-yard touchdown pass by Allen to Bills TE Tommy Sweeney. In the fourth quarter, with help from a 20-yard reception by WR A.J. Henry rushed five times for 29 yards and one three-yard rushing touchdown as the Titans retook the lead, 24-23. Buffalo built a 6-0 lead with a field goal in each of the first two quarters. The Bills opened up the second half with a 52-yard field goal to make it a 23-17 contest. On the Bills’ first play of their next drive, Allen was intercepted by S Kevin Byard who returned the ball to the Buffalo 11-yard line.

Poyer signed a revised contract which will give him more incentives in 2022. His potential extension still waits, but it could be a step in the right direction.

"I would love to be here long term… His potential extension still waits, but it could be a step in the right direction. Since then, Poyer has spoken for himself.

It's fair to say Bills DE A.J. Epenesa hasn't had the impact he or the team would have wanted as a former second-round pick. Part of the issue has been ...

Patriots RB [Damien Harris](https://www.pro-football-reference.com/players/H/HarrDa06.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-)said they aren’t as good right now as they’re going to be, while WR [Jakobi Meyers](https://www.pro-football-reference.com/players/M/MeyeJa01.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-)said: “Confidence isn’t an issue…[but] I question what the plan is sometimes and how we’re going to attack.” [Matthew Slater](https://www.pro-football-reference.com/players/S/SlatMa00.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-)has played his entire career in New England, but took a free agent visit with the Steelers in 2018: “That was a unique time in my career. You can do it, you can get out of this hole.’ If he can get his team to match his commitment, it’s going to work out for him. You can’t do it.’ You need somebody, even when the chips are against you, to show you, ‘Hey, here’s the way to get out of this. I got to the point that I couldn’t gain that weight back, or I was really struggling.” One of his former players, ex-NFL CB Now he has to make it consistent and not just another flash in the pan. But amidst the pandemic away from the team’s facility, Epenesa couldn’t stop losing weight and fell all the way down to the 240-pound range. Rarely. Buffalo wanted him to slim down from his college playing weight of 280 pounds. Part of the issue has been getting Epenesa to a settled playing weight. Epenesa](https://www.pro-football-reference.com/players/E/EpenAJ00.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-) hasn’t had the impact he or the team would have wanted as a former second-round pick.

El defensive tackle de los Titans Tennessee Jeffery Simmons está esperando enfrentar a su excompañero Rodger Saffold, quien firmó este verano con los Bills ...

Los Titans se han llevado los últimos dos en Nashville con Simmons ayudando a contener al quarterback de los Bill Josh Allen en cuarta y gol para que Tennessee ganara. Allen ha enfrentado a Tennessee en todas sus temporadas en la NFL y cree que esa familiaridad les ayudará. Inició su carrera con los Rams de Los Ángeles y venció las últimas dos temporadas a los Rams con los Titans.

NFL.com's Michael Baca breaks down what to watch for in Monday night's double dip with the Buffalo Bills hosting the Tennessee Titans and the Minnesota ...

Gardner-Johnson](https://www.nfl.com/players/chauncey-gardner-johnson/)and [James Bradberry](https://www.nfl.com/players/james-bradberry/). ABC](https://www.nfl.com/games/vikings-at-eagles-2022-reg-2) [Justin Jefferson](https://www.nfl.com/players/justin-jefferson/)goes to Philadelphia. [Caleb Farley](https://www.nfl.com/players/caleb-farley/)re-enters the fray. Brown](https://www.nfl.com/players/a-j-brown/)era. Brown](https://www.nfl.com/players/a-j-brown/), the Jefferson storyline lingers for Philadelphia. The interior wreckers of the Bills defensive line will be without [Ed Oliver](https://www.nfl.com/players/ed-oliver/)(ankle; out) and [Tim Settle](https://www.nfl.com/players/tim-settle/)(calf; doubtful) against the Titans, however, and the absences could be a factor in thwarting a Titans team that relishes off the run. Although WRs [Kyle Philips](https://www.nfl.com/players/kyle-philips/)(six receptions, 66 yards) and [Treylon Burks](https://www.nfl.com/players/treylon-burks/)(three receptions, 55 yards) played well in their debuts, it surely wasn’t in the game plan to have both rookies lead all Titans pass catchers. [upset loss](https://www.nfl.com/games/giants-at-titans-2022-reg-1)to the Giants. That doesn’t mean Allen won’t be a part of it (leads Bills with 56 rushing yards), but [Devin Singletary](https://www.nfl.com/players/devin-singletary/)and [Zack Moss](https://www.nfl.com/players/zack-moss/)are poised to find themselves in a big spot as the Titans tend to manufacture rock fights. [Robert Woods](https://www.nfl.com/players/robert-woods/)’ first game as a Titan barely made the box score (one reception, 13 yards) and Tannehill’s two touchdown throws on the day were to running back [Dontrell Hilliard](https://www.nfl.com/players/dontrell-hilliard/), who has been ruled out versus Buffalo. [Derrick Henry](https://www.nfl.com/players/derrick-henry/)’s 82 scrimmage yards (all rushing) led the entire team, and the lack of a vertical threat to compliment their best player was a major factor. [Josh Allen](https://www.nfl.com/players/josh-allen-4/)certainly remembers [the last one](https://www.nfl.com/news/josh-allen-a-lot-of-shoulda-coulda-wouldas-will-fuel-bills-after-last-second-los), which ended on his [failed 4th-and-1 sneak](https://www.nfl.com/videos/can-t-miss-play-tennessee-tough-titans-d-prevails-with-game-winning-stop-on-four)near the goal line.

SportsLine simulated Tennessee Titans vs. Buffalo Bills during the Monday Night Football doubleheader 10000 times.

[Visit SportsLine now to see which side of the Titans vs. [Derrick Henry](/nfl/players/2061188/derrick-henry/) is a tank in the backfield. Titans](https://www.sportsline.com/nfl/game-forecast/NFL_20220919_TEN@BUF/) and just locked in its picks and NFL predictions. SportsLine's model is leaning Over on the total, with the teams projected to combine for 52 points. Now, here are several [NFL odds](https://www.sportsline.com/nfl/odds/) and betting lines for Titans vs. [You can head to SportsLine now to see the model's picks](https://www.sportsline.com/insiders/titans-vs-bills-nfl-lines-odds-picks-proven-nfl-model-reveals-predictions-for-a-monday-night-football-matchup/#ttag=09172022_agg_cbssports_picks_football_nfl_model_titansbillsMNFmodel). The model enters Week 2 of the 2022 NFL season on an incredible 139-98 run on top-rated [NFL picks](/nfl/picks/experts) that dates back to the 2017 season. Buffalo had a commanding contest in the Week 1 win over the Rams. Buffalo is favored by 10 points in the latest Bills vs. Buffalo had a dominant performance in Week 1, topping the [Los Angeles Rams](https://www.cbssports.com/nfl/teams/LAR/los-angeles-rams/), 31-10. Meanwhile, Tennessee gave up a 13-point lead and fell to the [New York Giants](https://www.cbssports.com/nfl/teams/NYG/new-york-giants/) 21-20 in Week 1. Titans odds from Caesars Sportsbook, and the over/under is set at 48.

Bengals WR Ja'Marr Chase was fined twice for unsportsmanlike conduct in the Week 1 loss to the Steelers, with one fine for $13,261 and the second for ...

( [Mike Garafolo](https://twitter.com/MikeGarafolo/status/1571536899994533890?s=20&t=gHzB3Omq4ICfk9OixTiQqA)) [Jonathan Cooper](https://www.pro-football-reference.com/players/C/CoopJo01.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-)was fined $4,723 for taunting in the Week 1 loss to the Seahawks. [Javonte Williams](https://www.pro-football-reference.com/players/W/WillJa10.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-)was fined $11,194 for unnecessary roughness in the Week 1 loss to the Seahawks. [Stefon Diggs](https://www.pro-football-reference.com/players/D/DiggSt00.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-)was fined $10,609 for unsportsmanlike conduct for taunting Rams CB [Jalen Ramsey](https://www.pro-football-reference.com/players/R/RamsJa00.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-), although no flag was thrown. ( [Tom Pelissero](https://twitter.com/TomPelissero/status/1571214793691828225?s=20&t=gHzB3Omq4ICfk9OixTiQqA)) [Ja’Marr Chase](https://www.pro-football-reference.com/players/C/ChasJa00.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-)was fined twice for unsportsmanlike conduct in the Week 1 loss to the Steelers, with one fine for $13,261 and the second for $10,609. [Gabriel Davis](https://www.pro-football-reference.com/players/D/DaviGa01.htm?utm_campaign=Linker&utm_source=direct&utm_medium=linker-)turned his ankle on a non-contact play in practice. I’m just excited for this year, excited to be with this coaching staff, excited to be playing of course with Russ and just excited to take advantage of the opportunities I’m going to have this year.” But now that we have a great coaching staff, great quarterback putting me in position to be successful and now it’s up to me to take advantage of those opportunities.” It was Jeudy’s first touchdown since his rookie year after going scoreless throughout all of the 2021 season. Although the Broncos lost in Week 1, Jeudy’s 67-yard touchdown pass is a sign that he might be putting things together. ( [Tom Pelissero](https://twitter.com/TomPelissero/status/1571213412843110405?s=20&t=gHzB3Omq4ICfk9OixTiQqA))

Buffalo opens as a favorite over Miami, but maybe not as big a favorite as expected.

The Bills do not play until tomorrow night, hosting the [Tennessee Titans](https://www.musiccitymiracles.com/) in a Monday Night Football contest, so there is a chance the line could move following that contest. Assuming the Dolphins are getting the standard three-point home-field advantage, the oddsmakers see Buffalo as just over a touchdown better than Miami. While the celebrating is still ongoing, there is also now a chance to look at next week’s game as the Dolphins welcome AFC East rivals, the [Buffalo Bills](https://www.buffalorumblings.com/), into Miami. The Bills are the consensus favorite to get to the [The Bills are listed as a 4.5-point favorite](https://dksb.sng.link/As9kz/30m1?_dl=https%3A%2F%2Fsportsbook.draftkings.com%2Fgateway%3Fs%3D671872939%26wpcid%3D163148%26wpcn%3DOpeningOdds%26wpsrc%3DVox%26wpcrid%3DOdds&pcid=163148&pscn=Odds&pcrn=OpeningOdds&psn=Vox) by [DraftKings Sportsbook](https://dksb.sng.link/As9kz/30m1?_dl=https%3A%2F%2Fsportsbook.draftkings.com%2Fgateway%3Fs%3D671872939%26wpcid%3D163148%26wpcn%3DOpeningOdds%26wpsrc%3DVox%26wpcrid%3DOdds&pcid=163148&pscn=Odds&pcrn=OpeningOdds&psn=Vox) Sunday night after being 4.5-point favorites before the Dolphins-Ravens game. [Miami Dolphins](https://www.thephinsider.com/) are coming off a massive win Sunday afternoon, coming back from a 21-point deficit in the fourth quarter to beat the [Baltimore Ravens](https://www.baltimorebeatdown.com/) 42-38.

One of the more interesting storylines for this week is the Titans facing their old buddy, guard Rodger Saffold, who is now playing for the Bills after ...

Says he is living his running back dreams through Henry. [#Titans]running back Derrick Henry and also says he has a better 40 time. [September 14, 2022] “I’m not expecting to see kind of the mishaps that happened last game,” he continued. “I hate to say this: But when… Henry has a special ability to do that.

The Titans face the Buffalo Bills on Monday night at Highmark Stadium in Orchard Park, New York. Senior Writer and Editor Jim Wyatt takes a look at six ...

The Titans need to stiffen up inside the 20 and hold the Bills to field goals. The last thing they need to do is make it easier for a good Bills team. One of the biggest disappointments – and surprises – in Sunday's season opener was the leaky run defense by the Titans. Last week it was running back Dontrell Hilliard who produced a pair of scores, but with Hilliard out for Monday's game, the Titans will need other players to step up against the Bills. For starters, a big night for Henry would allow the Titans to control the ball and the clock while also slowing down Buffalo's pass rush. The challenge for the Titans offensive line – including rookie right tackle Nicholas Petit-Frere – will be much different against the Bills.

Buffalo Bills, Tennessee Titans Week 2 bets to place on props on Monday Night Football.

The Bills could very well win, but the Titans should cover. [Tipico Sportsbook](https://www.tipico.com/us) Win or loss, he’s put up solid numbers against Tennessee because of the volume of opportunities Buffalo’s QB gets. He should have a couple of grabs to push this total. [five total scores](https://billswire.usatoday.com/lists/buffalo-bills-tennessee-titans-storylines-derrick-henry-josh-allen/). But in his past two games against Buffalo, the Tennessee rusher has

The Buffalo Bills host the Tennessee Titans in Orchard Park Monday Night as both teams usher in Week 2 of their respective schedules.

Hungry for more Buffalo Bills news? Are you a member of Bills Mafia? [HERE](https://www.si.com/nfl/bills/news) Despite his quiet 82 rushing yards in the Titans' Week 1 loss to the Giants, Buffalo has to expect the running game to be a focus for Tennessee. 1 against the pass. The Bills face a motivated Tennessee Titans team on Monday night from Highmark Stadium. the Titans.](https://sportsbook.fanduel.com/navigation/nfl) [Ken Dorsey's first game as Buffalo's offensive coordinator](https://www.si.com/nfl/bills/news/buffalo-ken-dorsey-coach-los-angeles-la-rams-josh-allen-heckuva-game-stefon-diggs): That’s a recipe for success.” “I think Coach Dorsey called a heckuva game,” Allen said. Wide receiver Gabe Davis sustained an ankle injury at week’s end, and he’s officially listed as questionable for the game. [SI SportsBook](https://www.sisportsbook.com/football/usa/nfl/tennessee-titans-buffalo-bills-e-438393/)