Bills vs Rams

The star-studded affair marks the first-ever meeting between superstar quarterbacks Matthew Stafford and Josh Allen.

[without the injured cornerback Tre'Davious White](https://www.si.com/nfl/bills/news/buffalo-tre-tredavious-white-torn-acl-pup-list-roster-53-man-update-move). [“I can never hate L.A.," Miller said.](https://www.si.com/nfl/rams/news/los-angeles-von-miller-buffalo-bills-justin-hollins-sean-mcvay-terrell-lewis-week1-super-bowl) "They came and got me at a time when I really needed that. "Those are the scariest things is when you have a quarterback that when everything's right and in rhythm he's basically automatic, but then he can also beat you off-schedule," McVay said. Motivation is sky-high for a fiery Bills team that is still feeling the effects of last season's heart-breaking AFC Divisional loss. Expectations are high for the 26-year-old Allen, who has become one of the league's premier dual-threat signal-callers as he begins what could be a MVP-caliber season. The star-studded affair marks the first-ever meeting between superstar quarterbacks Matthew Stafford and Josh Allen.

We take a look at the best bets available for Bills vs. Rams Week 1 matchup available on DraftKings Sportsbook, including our favorite player prop.

Physically present in AZ/CO/CT/IL/IN/IA/KS/LA(select parishes)/MI/NH/NJ/NY/OR/PA/TN/VA/WV/WY only. If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL/IN/MI/NJ/PA/WV/WY), 1-800-NEXT STEP (AZ), 1-800-522-4700 (CO/KS/NH), 888-789-7777/visit ccpg.org/chat (CT), 1-800-BETS OFF (IA), 1-877-770-STOP (7867) (LA), 877-8-HOPENY/text HOPENY (467369) (NY), visit OPGR.org (OR), call/text TN REDLINE 1-800-889-9789 (TN), ConnexOntario 1-866-531-2600 (ONT), or 1-888-532-3500 (VA).21+ (18+ NH/WY). [Los Angeles Rams](https://sportsbook.draftkings.com/teams/football/nfl/los-angeles-rams--odds) head coach Sean McVay has insisted that QB Matt Stafford’s lingering elbow pain will not affect his play at all in the home opener, but even at full strength, the Bills are going to be a real challenge. 1 in the NFL for the last 15 weeks of the regular season in 2021) became even stronger in the offseason with the addition of former Rams LB Von Miller. It’s a primetime game, and both offenses are going to be pulling out some creative playcalling to start the season off strong. The Bills also return star quarterback Josh Allen, who broke the record last postseason for the highest postseason passer ranking in NFL history.

Breaking down the on-field matchups for the Rams and Buffalo Bills ahead of the 2022 NFL season opener on Thursday at SoFi Stadium.

[Rams kicker Matt Gay](https://www.latimes.com/sports/rams/story/2021-01-13/matt-gay-rams-kicking-game) was voted to the Pro Bowl last season after making 32 of 34 field-goal attempts. [Cam Akers](https://www.latimes.com/sports/rams/story/2022-08-29/injured-cam-akers-darrell-henderson-running-backs-return-rams) and [Darrell Henderson](https://www.latimes.com/sports/rams/story/2022-08-29/injured-cam-akers-darrell-henderson-running-backs-return-rams) are the top running backs, but rookie Kyren Williams also could have a role. Isaiah McKenzie and Gabe Davis are other receivers in an offense that also features tight end [Dawson Knox](https://www.nfl.com/players/dawson-knox/) and running back [Devin Singletary](https://www.pro-football-reference.com/players/S/SingDe00.htm). [Rams](https://www.latimes.com/sports/rams) and the [Buffalo Bills](https://www.buffalobills.com/) match up heading into their game at 5:20 PST on Thursday at SoFi Stadium. New addition [Allen Robinson](https://www.latimes.com/sports/rams/story/2022-08-22/new-rams-receiver-allen-robinson-joint-practices-bengals) is regarded as one of the best at contested catches. [Cooper Kupp](https://www.latimes.com/sports/rams/story/2022-06-08/rams-agree-new-deal-receiver-cooper-kupp) led the NFL in catches, yards receiving and touchdown catches last season, and was the Super Bowl MVP. [Josh Allen](https://www.latimes.com/sports/story/2021-01-23/josh-allen-firebaugh-california-town-buffalo-bills-nfl) is among the most versatile quarterbacks, running an offense now under the direction of Ken Dorsey, who was promoted from quarterbacks coach after the New York Giants hired Brian Daboll as head coach. Allen’s top target is receiver [Stefon Diggs](https://www.pro-football-reference.com/players/D/DiggSt00.htm), who last season caught 103 passes, 10 for touchdowns. [Quarterback Matthew Stafford](https://www.latimes.com/sports/rams/story/2022-09-04/matthew-stafford-rams-cooper-kupp-offense-nfl) has been nursing tendinitis in his right elbow but appears to be at full strength. Troy Hill and David Long probably will start at corner with Ramsey. Last season, Allen passed for 36 touchdowns, with 15 interceptions, and rushed for 763 yards and six scores. The game will be shown on Ch.

In no way will the Los Angeles Rams get to ease into the 2022 season, not that they'll complain. As the defending Super Bowl champions, they get the honor ...

And for the Rams defense, the challenge is even greater. Fortunately, they won’t have to go up against Tre’Davious White, but this Bills team is as talented as any on the defensive side of the ball. The Rams are among the title favorites this year, but no team has better odds to win the Super Bowl than their Week 1 opponent, the Bills.

R.J. White is 44-33 on NFL picks involving Matthew Stafford, Cooper Kupp, and the Los Angeles Rams.

- Bills vs. [Visit SportsLine now to see which side of the Bills vs. Here are the [NFL odds](https://www.sportsline.com/nfl/odds/) and betting lines for Bills vs. Rams in the NFL Kickoff Game 2022? [Jordan Poyer](/nfl/players/1665374/jordan-poyer/), who missed the exhibition season because of a hyperextended elbow, is expected to play in Thursday's opener. The Rams' stalwart was named to the All-Pro first team for the first time in his career and earned AP Offensive Player of the Year honors, among numerous other accolades. [NFL picks](https://www.sportsline.com/nfl/picks/) against the spread. Rams](https://www.sportsline.com/nfl/game-forecast/NFL_20220908_BUF@LAR/) Week 1 matchup from every angle and released a confident against-the-spread selection. [You can head to SportsLine now to see White's pick](https://www.sportsline.com/insiders/bills-vs-rams-odds-line-spread-proven-nfl-expert-reveals-picks-for-2022-season-week-1-tnf-showdown/#ttag=08312022_agg_cbssports_picks_football_nfl_rjwhite_RamsBucsWeek1). The Bills are 2.5-point favorites and the over-under for total points scored is 53 in the latest Bills vs. Before locking any Rams vs. [Los Angeles Rams](https://www.cbssports.com/nfl/teams/LAR/los-angeles-rams/) will hope to keep that trend alive on Thursday when they meet the [Buffalo Bills](https://www.cbssports.com/nfl/teams/BUF/buffalo-bills/) in the 2022 [NFL](/nfl) Kickoff Game.

The team remedied this by bringing back Troy Hill from the Cleveland Browns and drafting four defensive backs in April's draft. Decobie Durant and Derion ...

Buffalo is too talented of a team to not keep this game close, but I’ve got to go with the defending champs in this one. But I think, for the Rams, winning Thursday’s game will come down to if their offense can keep up with Josh Allen. Poyer and Hyde are two of the league’s best safeties, but the Rams’ could take advantage of openings underneath to slowly chip away at the Buffalo defense en route to a win Dimmitt: It’s easy to say the typical coach cliches. Dimmitt: Though LA has one of the best cornerbacks in the league in Jalen Ramsey, the Rams secondary was arguably its weakest unit last season. Buffalo will still have Jordan Poyer and Micah Hyde on the back end, while first-round rookie corner Kaiir Elam could likely have his hands full.

SportsLine's model has simulated Buffalo Bills vs. Los Angeles Rams in the NFL Kickoff Game 2022 10000 times.

Los Angeles added to its embarrassment of riches by signing linebacker and six-time All-Pro [Bobby Wagner](/nfl/players/1631476/bobby-wagner/) from the division rival [Seahawks](https://www.cbssports.com/nfl/teams/SEA/seattle-seahawks/) in the offseason. Rams](https://www.sportsline.com/nfl/game-forecast/NFL_20220908_BUF@LAR/) in the NFL Kickoff Game 2022 10,000 times and just revealed its NFL expert picks and predictions. [Visit SportsLine now to see the Bills vs. Here are several [NFL odds](https://www.sportsline.com/nfl/odds/) and betting trends for Rams vs. [Cooper Kupp](/nfl/players/2006951/cooper-kupp/) is back after winning the receiving triple crown with 145 catches for 1,947 yards and 16 touchdowns last season. [You can head to SportsLine now to see its picks](https://www.sportsline.com/insiders/bills-vs-rams-lines-picks-proven-nfl-model-reveals-selections-for-2022-nfl-kickoff-game/#ttag=08292022_agg_cbssports_picks_football_nfl_model_billsramsmodel). [Buffalo Bills](https://www.cbssports.com/nfl/teams/BUF/buffalo-bills/) will visit the [Los Angeles Rams](https://www.cbssports.com/nfl/teams/LAR/los-angeles-rams/) in a blockbuster 2022 [NFL](/nfl) Kickoff Game on Thursday night. And which side of the spread cashes well over 50% of the time? Stafford won't have [Odell Beckham Jr](/nfl/players/1824823/odell-beckham-jr/). The Rams are coming off a [Super Bowl](/nfl/superbowl/) win, while the Bills are the preseason 2023 Super Bowl favorites at Caesars Sportsbook. Rams odds from Caesars Sportsbook, while the over/under for total points scored is 52. Buffalo is a 2.5-point favorite in the latest Bills vs.

The Buffalo Bills are coming to town with Super Bowl dreams of their own, and with former Rams linebacker Von Miller on their side along with quarterback Josh ...

However, this is one of the more difficult games on the schedule. Obviously the Rams also know a lot about how to game plan around Miller by the same experience, but if the Bills can find a way to use this storyline to their advantage, tonight's game might not be as close as it should. The Bills will lose if they score fewer points than the Rams. The Bills will win if they score more points than the Rams. Gabe Davis is the biggest X-Factor on offense. If you take out that storyline and the fact that the game is in Los Angeles, I would take the Bills. The Bills are a favorite to win the Super Bowl this season. On offense, the Bills upgraded in the trenches by adding former Rams offensive lineman Rodger Saffold. And on defense, the Bills signed former Rams linebacker Von Miller. What makes them different from the team that was a few play away from making it to the AFC Championship last season? The Bills will either win every game this season or lose very closely. Davis is proving to be a worthy No.

The reigning Super Bowl champion LA Rams will kick off the 2022 NFL season Thursday against one of the preseason favorites: the Buffalo Bills.

The Rams are returning mostly the same roster from last season, with one interesting storyline being the departure of edge rusher Von Miller, [who signed with the Bills](https://www.usatoday.com/story/sports/nfl/2022/03/16/buffalo-bills-von-miller-agree-free-agent-contract/7069452001/) in March. Gannett may earn revenue from Tipico for audience referrals to betting services. Tipico has no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. In his place, the Bills have appointed Ken Dorsey, who has been with the franchise since 2019, as the new offensive coordinator. [in January](https://www.usatoday.com/story/sports/nfl/giants/2022/01/28/brian-daboll-hired-head-coach-new-york-giants/9261438002/). Los Angeles would be looking to repeat after it

1. Bills' pass rush pressuring Matthew Stafford into turnovers · 2. Van Jefferson's injury · 3. Coleman Shelton at right guard · 4. Bills' wide receiver depth · 5.

The single biggest threat to the Rams’ chances of winning this game is Allen. He’ll be the responsibility of Bobby Wagner, Ernest Jones and the safeties, but this entire receiving corps is tough to defend. Shelton will be someone to watch tonight against the Bills. This could be a great opportunity for him to show off his speed and make a big play or two like he did in training camp, but he’s never caught an NFL pass, so there’s a real lack of experience without Jefferson available. Their opening opponent this season, the Buffalo Bills, will be the complete opposite of a cake walk. 3 receiver and with him being out, a combination of Ben Skowronek and Tutu Atwell will be forced to fill in.

Our staff of betting analysts lay out their favorite picks for the NFL season opener between the Buffalo Bills and Los Angeles Rams.

and Robert Woods hurts, but Allen Robinson comes in to ease the loss and forces Sean McVay to balance out the attack with a capable running back committee. He regressed to the middle of the pack in EPA and Turnover Rate last season, a statistical image of his bad habits. The Rams’ defense was good against tight ends last year, giving up only two touchdowns to the position. He was WR13 in fantasy at the time of the injury. While I am never a fan of taking an underdog at +2.5, I will instead be throwing them into a Wong Teaser with Dallas to give me both teams at +8.5. If there’s a weakness on this Bills team, it’s at the cornerback position. Analyzing the market’s view and outcomes of each team in those scenarios presents a valuable entry point into the game, and I will be playing the over at 51.5 on FanDuel and would play it to 52. After being stuck in purgatory — erm, Chicago — Robinson joins a high-powered offense with which I expect a big season opener from the 29-year-old. [Titans](https://www.actionnetwork.com/nfl/odds/tennessee-titans), Bucs and twice against the [Chiefs](https://www.actionnetwork.com/nfl/odds/kansas-city-chiefs) (once in the playoffs). The following week, the Rams played the Cards at home on a total of 54 – their second-highest of the year – with that game also going over by a field goal. As the season went on, Rams totals gradually decreased to around 47-48, but there’s an overall trend with their game outcomes. Now, the Bills are -2.5 at most sportsbooks.

The two women threw a pink smoke bomb as they made their way onto the field.

The two women carried red flares and one of them threw a pink smoke bomb onto the turf. This certainly isn't the first time that Direct Action Everywhere has managed to make a statement during a sporting event. [defending Super Bowl champion Los Angeles Rams taking on the Buffalo Bills](https://www.cbssports.com/nfl/news/rams-vs-bills-score-josh-allen-throws-for-three-tds-runs-for-one-as-buffalo-dominates-second-half/live/).

Von Miller (40). Buffalo Bills vs Los Angeles Rams, Week 1, September 8, 2022 at SoFi Stadium. 1 – D- ...

As a result, just about every receiving target on the roster got involved in the passing game. "We felt like their corners were really looking in at the quarterback and Diggs just ran a heck of a route," said Josh Allen. Josh was very patient, and the receivers were running crisp routes." The Bills offense had to be patient in the early stages of the game as the Los Angeles defense made certain not to give up any big plays. So, I was glad I was able to be put in that position." "It's great when there's a time to put a team away and they're putting the trust in you to make the play and you make it," said Davis. "We knew on the back end if we just gave them an extra half second and get Stafford to blink, they were going to get there, so they did a hell of a job. "I just did what Josh told me to do," said Diggs of the play. When Buffalo came out in the second half however, they were determined to regain their early 10-point lead and put the game away. Three plays later Josh Allen took a four-yard run into the end zone and suddenly the Bills were up two scores (24-10). "We've got a great unit and we've got a great coaching staff as well. "You've got to be able to get there with four and we were able to do that," said head coach Sean McDermott of the pass rush putting heat on the quarterback.

INGLEWOOD, Calif. -- — The Buffalo Bills have fallen short in enough playoff games in recent years to know the season is long and the opener doesn't mean ...

[Ed Oliver](https://www.espn.com/nfl/player/_/id/4039303/ed-oliver) injured his ankle in the first half and tried to play through it, but couldn't do much. Along with the banner to celebrate last February's title, the Rams also hung a banner in the south rafters at SoFi Stadium honoring the 1999-2000 Super Bowl champions from the St. ... The Rams played without WR [Van Jefferson](https://www.espn.com/nfl/player/_/id/3930066/van-jefferson), who had knee surgery early in training camp after starting 21 games last season. He tied Drew Brees as the fastest to the mark, doing it in 183 games. “You’ve got the two top guys in the NFL competing against each other,” Davis said of Diggs and Ramsey. They also lost by the second-biggest margin in league history for a Super Bowl winner beginning its next season; Baltimore lost by 22 to Denver in 2013. “We’re going to celebrate this win, because you have to, but then we’re going to go back to the lab.” [Josh Allen](https://www.espn.com/nfl/player/_/id/3915239/josh-allen) passed for 297 yards while accounting for four touchdowns, [Miller had two of Buffalo’s seven sacks](https://www.nfl.com/videos/von-miller-gets-his-first-sack-as-a-bill-on-rams-first-drive), and the Bills stamped themselves as a clear contender for the Rams’ crown with a 31-10 victory over Los Angeles on Thursday night. [an exceptional toe-tapping TD catch](https://www.nfl.com/videos/can-t-miss-play-first-toe-tap-td-catch-of-22-is-a-kupp-masterpiece) three minutes before halftime. Los Angeles trailed 17-10 after three quarters, but Buffalo ran away with two lengthy TD drives early in the fourth. “Very humbling night, but one where you look yourself in the mirror and say you have to be better,” McVay said. Miller came through, but he was just one contributor on a night when Buffalo didn't even need to blitz once to keep Stafford in check. Los Angeles could not keep up with Allen’s creative playmaking or the Bills’ pass rush, and its only major offseason addition on offense — receiver Allen Robinson — had one catch on two targets.

Josh Allen reacts after defeating the Los Angeles Rams at SoFi Stadium on September 8. (CNN) If there was any doubt about the Buffalo Bills ...

"I've got to do better, there were a lot of decisions that I made that I felt like didn't put our players in good enough spots. We did some good things but got to get back in the lab." And seven months after winning February's Super Bowl, the Rams returned. We got to continue to get better on offense. Miller finished Thursday's win with two sacks and three tackles for a loss. We did some good things, we had four turnovers.